The carbon and proton spectra of the title compound were completely assigned on the basis of COSY, HETCOR, DEPT and selective single-frequency decoupling experiments. The validity of the proton-proton coupling constants determination was checked by computer simulation.
Base-catalyzed C-2 exchange and epimerization of cocaine analogs: methyl 3.beta.-substituted 8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylates
✍ Scribed by Casale, John F.; Lewin, Anita H.; Bowen, J. Phillip; Carroll, F. I.
- Book ID
- 126446215
- Publisher
- American Chemical Society
- Year
- 1992
- Tongue
- English
- Weight
- 815 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0022-3263
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The synthesis of a d'carbapenem and two ,?-lactams possessing a Br-atom at the N-substituting center not involved in the lactam ring and bearing the carboxyl group is described. The ,?-lactams having this kind of Br-substitution are more susceptible to nucleophilic attack than those having a conjuga
## Abstract The synthesis of potential hydroxy metabolites of the brain imaging agents methyl (1__R__,2__S__,3__S__,5__S__)‐3‐(4‐iodophenyl)‐8‐methyl‐8‐azabicyclo[3.2.1]octane‐2‐carboxylate and methyl (1__R__,2__S__,3__S__,5__S__)‐3‐(4‐iodophenyl)‐8‐(3‐fluoropropyl)‐8‐azabicyclo[3.2.1]octane‐2‐carb