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Basal Regulatory Promoter Elements of the hsp27 Gene in Human Breast Cancer Cells

✍ Scribed by Steffi Oesterreich; Eileen Hickey; Lee A. Weber; Suzanne A.W. Fuqua

Book ID
115578443
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
645 KB
Volume
222
Category
Article
ISSN
0006-291X

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Since the small heat shock protein hsp27 enhances both growth and drug resistance in breast cancer cells, and is a bad prognostic factor in certain subsets of breast cancer patients, we have characterized the transcriptional regulation of hsp27, with the long-term goal of targeting its expression cl