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Bared essentials of CDK2 and cyclin E

โœ Scribed by Roberts, James M; Sherr, Charles J


Book ID
109918774
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
101 KB
Volume
35
Category
Article
ISSN
1061-4036

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Concurrent amplification of cyclin E and
โœ Kenji Kitahara; Wataru Yasui; Hiroki Kuniyasu; Hiroshi Yokozaki; Yoshihiko Akama ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 507 KB

## The genetic changes of cyclin A, DI, E and CDK2 were examined in human colorectal carcinomas by Southern-blot analysis. Gene amplification of cyclin E was detected in 5 of 53 (9.4%) primary colorectal carcinoma tissues. Interestingly, in 3 of 5 tumors showing cyclin E gene amplification, the CD