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Barbiturate shift as a tool for determination of efficacy of benzodiazepine-receptor ligands

✍ Scribed by Tage Honoré; Mogens Nielsen; Claus Braestrup

Book ID
115878528
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
365 KB
Volume
100
Category
Article
ISSN
0014-2999

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Biotinylated 1012-S conjugate as a probe ligand for benzodiazepine receptors: Characterization of receptor binding sites and receptor assay for benzodiazepine drugs
✍ Toshifumi Takeuchi; Shunitz Tanaka; Garry A. Rechnitz 📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 365 KB

A nonisotopic receptor assay using the biotin-1012-S conjugate was developed and the usefulness of this conjugate as a probe ligand for the benzodiazepine receptor was evaluated. The conjugate was incubated in a receptor suspension, and then the concentration of free conjugate in the supernatant was