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A synthetic non-benzodiazepine ligand for benzodiazepine receptors: A probe for investigating neuronal substrates of anxiety

✍ Scribed by Arnold S. Lippa; Joseph Coupet; Eugene N. Greenblatt; Claire A. Klepner; Bernard Beer


Book ID
113218017
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
716 KB
Volume
11
Category
Article
ISSN
0091-3057

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A nonisotopic receptor assay using the biotin-1012-S conjugate was developed and the usefulness of this conjugate as a probe ligand for the benzodiazepine receptor was evaluated. The conjugate was incubated in a receptor suspension, and then the concentration of free conjugate in the supernatant was