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Balancing repair and tolerance of DNA damage caused by alkylating agents

✍ Scribed by Fu, Dragony; Calvo, Jennifer A.; Samson, Leona D.

Book ID
109948859
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
955 KB
Volume
12
Category
Article
ISSN
1474-1776

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## Abstract DNA damage was evaluated by flow cytometric (FCM) analysis of cells treated with L‐phenylalanine mustard (L‐PAM) and stained with anti‐DNA monoclonal antibody (MAb) F7–26. DNA damage was rapidly repaired, as indicated by the loss of DNA immunoreactivity after removal of L‐PAM. Two types