Alzheimer's disease cells exhibit defective repair of alkylating agent—induced DNA damage

Comparison of DNA damage in plants as me

Comparison of DNA damage in plants as measured by single cell gel electrophoresis and somatic leaf mutations induced by monofunctional alkylating agents

✍ Tomáš Gichner; Ondřej Ptáček; Diana A. Stavreva; Michael J. Plewa 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 153 KB 👁 2 views

The use of single cell gel electrophoresis (SCGE) has recently been applied to plant systems. We optimized the experimental conditions for SCGE analysis using nuclei isolated from different tissues of intact plants. Concentration-response curves of genomic DNA migration were analyzed in intact plant