Synthesis of an enantiomerically pure st
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Schrötter, Eberhard ;Weidner, Judith ;Schick, Hans
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Article
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1991
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John Wiley and Sons
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English
⚖ 139 KB
## Abstract 1,3‐Dihydroxy‐3‐methyl‐2‐butanone (1), accessible in 5 steps from 2‐methyl‐3‐butyn‐2‐ol, is reduced by baker's yeast to (__R__)‐(+)‐3‐methyl‐1,2,3‐butanetriol (2) with a high enantioselectivity. This chiral building block for the synthesis of various sterols with a modified side chain t