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Bacterial superantigen signaling via HLA class II on human B lymphocytes

✍ Scribed by N.A. Mooney; L. Ju; C. Brick-Ghannam; D.J. Charron


Book ID
118384994
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
887 KB
Volume
31
Category
Article
ISSN
0161-5890

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Signal transduction via HLA class-ll antigens has been studied using human resting B lymphocytes and monoclonal anti-HLA class-ll antibodies. An increased intracellular calcium flux, phosphatidylinositol biphosphate hydrolysis and activation of protein kinase C have all been observed following signa