Bacterial antibodies in HLA-B27+ healthy individuals
β Scribed by Paavo Toivanen; Saija Koskimies; Kaisa Granfors; Erkki Eerola
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 278 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0004-3591
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## Objective: To examine whether mica (major histocompatibility complex [mhc] class i-related chain gene a) confers additional susceptibility for seronegative spondylarthropathies in hla-b27 positive japanese individuals. ## Methods: A polymerase chain reaction-single-strand conformation polymorp
## Abstract The present study was performed on 61 HLAβB27 positive firstβdegree relatives and 40 HLAβB27 negative relatives of 20 HLAβB27 positive probands with ankylosing spondylitis (AS). Of 24 HLAβB27 positive relatives 45 years or older, 21% had AS and 38% sacroiliitis. The HLAβB27 negative rel