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B-type natriuretic peptide and wall stress in dilated human heart

✍ Scribed by P. Alter; H. Rupp; M. B. Rominger; A. Vollrath; F. Czerny; J. H. Figiel; P. Adams; F. Stoll; K. J. Klose; B. Maisch

Publisher
Springer
Year
2008
Tongue
English
Weight
569 KB
Volume
314
Category
Article
ISSN
0300-8177

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## Abstract Cardiac fibroblasts (CFs) regulate myocardial remodeling by proliferating, differentiating, and secreting extracellular matrix (ECM) proteins. B‐type natriuretic peptide (BNP) is anti‐fibrotic, inhibits collagen production, augments matrix metalloproteinases, and suppresses CF prolifera