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Use of Nesiritide (Human B-Type Natriuretic Peptide) in Infants Following Cardiac Surgery

✍ Scribed by J. M. Simsic; V. S. Reddy; K. R. Kanter; P. M. Kirshbom; J. M. Forbess

Publisher
Springer
Year
2004
Tongue
English
Weight
87 KB
Volume
25
Category
Article
ISSN
0172-0643

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## Abstract Cardiac fibroblasts (CFs) regulate myocardial remodeling by proliferating, differentiating, and secreting extracellular matrix (ECM) proteins. B‐type natriuretic peptide (BNP) is anti‐fibrotic, inhibits collagen production, augments matrix metalloproteinases, and suppresses CF prolifera