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B-Raf mutation: A key player in molecular biology of cancer

✍ Scribed by Rahman, M.A.; Salajegheh, A.; Smith, R.A.; Lam, A.K.-Y.

Book ID: 121384113
Publisher: Elsevier Science
Year: 2013
Tongue: English
Weight: 534 KB
Volume: 95
Category: Article
ISSN: 0014-4800
DOI: 10.1016/j.yexmp.2013.10.005

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## Abstract Mutations in the __B‐raf__ gene have been reported in a number of human cancers, including melanoma and lung cancer. More than 80% of the reported B‐raf mutations were V599E; however, non‐V599E mutations have been frequently found in non‐small cell lung cancers as compared with melanoma

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