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B cells regulate autoimmunity by provision of IL-10

✍ Scribed by Fillatreau, Simon; Sweenie, Claire H.; McGeachy, Mandy J.; Gray, David; Anderton, Stephen M.

Book ID
109923528
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
703 KB
Volume
3
Category
Article
ISSN
1529-2908

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## Abstract IL‐10‐producing regulatory B cells have been identified in mice and shown to downregulate inflammation, making them potentially important for maintenance of tolerance. In this study, we isolated B cells from human blood and spleen, and showed that after a short period of __ex vivo__ sti