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B cells can prime naive CD4+ T cells in vivo in the absence of other professional antigen-presenting cells in a CD154-CD40-dependent manner

✍ Scribed by Daniel Rodríguez-Pinto; José Moreno


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
313 KB
Volume
35
Category
Article
ISSN
0014-2980

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## Abstract The basis of the adjuvant effect of IL‐1 on the clonal expansion of Ag‐specific CD4 T cells was measured __in vivo__ using the TCR transgenic T cell adoptive transfer method. Injection ofAg plus IL‐1 caused naive CD4 T cells to proliferate to a greater extent than did injection of Ag al