The advantage of residualizing radiolabe
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M. Jules Mattes; Lisa B. Shih; Serengulam V. Govindan; Robert M. Sharkey; Gaik L
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Article
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1997
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John Wiley and Sons
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French
⚖ 104 KB
CD22 antibodies (Abs) bound to B-cell lymphomas are known to be internalized and catabolized rapidly. Therefore, it would be expected that use of CD22 as a target for radioimmunotherapy should be enhanced by the use of "residualizing" radiolabels, which are trapped within the cell after catabolism o