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B cell-targeted therapy with anti-CD20 monoclonal antibody in a mouse model of Graves' hyperthyroidism

โœ Scribed by I. Ueki; N. Abiru; M. Kobayashi; M. Nakahara; T. Ichikawa; K. Eguchi; Y. Nagayama

Book ID
108701326
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
388 KB
Volume
163
Category
Article
ISSN
0009-9104

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โœ M. Jules Mattes; Lisa B. Shih; Serengulam V. Govindan; Robert M. Sharkey; Gaik L ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 104 KB

CD22 antibodies (Abs) bound to B-cell lymphomas are known to be internalized and catabolized rapidly. Therefore, it would be expected that use of CD22 as a target for radioimmunotherapy should be enhanced by the use of "residualizing" radiolabels, which are trapped within the cell after catabolism o