✦ LIBER ✦

“B” cell origin of malignant cells in a case of american burkitt's lymphoma characterization of cells from a pleural effusion

✍ Scribed by Richard A. Binder; Judith A. Jencks; Byungkyu Chun; Charles E. Rath

Publisher: John Wiley and Sons
Year: 1975
Tongue: English
Weight: 739 KB
Volume: 36
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(197507)36:1<161::aid-cncr2820360114>3.0.co;2-p

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✦ Synopsis

Ninety-eight percent of the cells isolated from a malignant pleural effusion in a case of American Burkitt's lymphoma showed membrane fluorescence to antihuman IgM antisera, while only 2% of the cells formed spontaneous rosettes with sheep red blood cells. It is concluded that the Burkitt cells in the malignant effusion are derived from bursal equivalent lymphocytes. Epstein-Barr (E-B) viral titers to both viral capsule antigen and early antigen were not elevated. The significance of these findings is discussed.

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