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B-cell-depleting Therapy in Systemic Lupus Erythematosus

✍ Scribed by Manuel Ramos-Casals; Iñaki Sanz; Xavier Bosch; John H. Stone; Munther A. Khamashta


Book ID
116213262
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
698 KB
Volume
125
Category
Article
ISSN
1555-7162

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## Abstract ## Objective Autoantibody production in patients with systemic lupus erythematosus (SLE) is associated with abnormalities of B cell function and phenotype. Clinical responses to B cell depletion therapy (BCDT), based on rituximab, are encouraging. Therefore, we undertook this study to