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Prolonged effects of short-term anti-CD20 B cell depletion therapy in murine systemic lupus erythematosus

✍ Scribed by Kai W. Bekar; Teresa Owen; Robert Dunn; Travis Ichikawa; Wensheng Wang; Roger Wang; Jennifer Barnard; Sean Brady; Sarah Nevarez; Bruce I. Goldman; Marilyn Kehry; Jennifer H. Anolik


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
796 KB
Volume
62
Category
Article
ISSN
0004-3591

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Objective. To analyze changes in autoantibodies occurring in patients with systemic lupus erythematosus (SLE) treated with 4 infusions of the chimeric anti-tumor necrosis factor ␣ (TNF␣) antibody infliximab. Methods. In an open-label safety study, 7 patients with SLE were treated with infliximab at