B lymphocytes encounter antigen within the body, which causes them to undergo clonal expansion, affinity maturation and differentiation to antibody-forming cells. How they come into contact with the immunogen, and the subsequent response induced is the subject of several recent reports.
B cell activation, tolerance and antigen-presenting function
β Scribed by Philip D Hodgkin; Antony Basten
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 975 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0952-7915
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Exposure to haptens initiates a series of immune and inflammatory reactions that cause migration of epidermal Langerhans cells (LC) to draining lymph nodes, antigen processing, and presentation to T cells. In the present study, the antigen-presenting cell (APC) function of epidermal cells (EC) follo
Fc receptors are a family of membrane-associated and soluble glycoproteins that mediate a vast array of functions triggered by immune complexes. The structures of murine and human Fc gamma and Fc epsilon receptors have been elucidated and the motifs involved in the activities that they mediate chara
To summarize, during the period under review there have been considerable advances in our understanding of how antigen is associated with MHC on the surface of a presenting cell. Basic rules which govern this association have been confirmed as including both the nature and the configuration of the a