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Aziridine biotransformation by microsomes and lethality to hepatocytes isolated from rat

✍ Scribed by Yoshiteru Hata; Masamichi Watanabe; Kanya Tonda; Masaharu Hirata


Book ID
113137057
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
728 KB
Volume
63
Category
Article
ISSN
0009-2797

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✍ JΓΌrg Reichen; Catherine Hoilien; Mysan Le; Richard H. Jones πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 English βš– 454 KB

To differentiate between the "intact" and "sick" cell hypo€he& explaining decreased clearance of endo-and xenobbtics, we meaeured uptake of taurocholate and OIlQBOill in hepatocytes isolated from cirrhotic rat liver. Cirrhouis was induced by chronic exposure of male Sprague-Dawley rats to phenobarbi