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Azabicyclic alcohols. VI. Azabicyclo [2.2.1]heptan-3-ol epimers

✍ Scribed by Spry, Douglas O.; Aaron, Herbert S.


Book ID
126075715
Publisher
American Chemical Society
Year
1969
Tongue
English
Weight
473 KB
Volume
34
Category
Article
ISSN
0022-3263

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The l-azabicyclo[2.2. I]heptan-3-exo-ol (2) was resolved by fractional crystallisation of its hydrogen tartrate salts. The enantiomers (+)-and (-)-2 were oxidised to the ketones (-)-4 and (+)-4, respectively (Scheme). CD spectroscopy suggested that (-)-4 possesses the (IR,4S)-configuration. This abs