Azabicyclic alcohols. VI. Azabicyclo [2.2.1]heptan-3-ol epimers
β Scribed by Spry, Douglas O.; Aaron, Herbert S.
- Book ID
- 126075715
- Publisher
- American Chemical Society
- Year
- 1969
- Tongue
- English
- Weight
- 473 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0022-3263
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The l-azabicyclo[2.2. I]heptan-3-exo-ol (2) was resolved by fractional crystallisation of its hydrogen tartrate salts. The enantiomers (+)-and (-)-2 were oxidised to the ketones (-)-4 and (+)-4, respectively (Scheme). CD spectroscopy suggested that (-)-4 possesses the (IR,4S)-configuration. This abs