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Azabicyclic alcohols. V. Synthesis and stereochemistry of the 1-azabicyclo[3.2.1]octanols

✍ Scribed by Thill, Bruce P.; Aaron, Herbert S.


Book ID
121434333
Publisher
American Chemical Society
Year
1968
Tongue
English
Weight
720 KB
Volume
33
Category
Article
ISSN
0022-3263

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## Abstract The azabicyclic __endo__ compound 3 was synthesized by reaction of enamine 1 with 2‐benzoyl‐1,3‐dichloropropane (2). The thermodynamically more stable __exo__ isomer 4 was obtained by epimerization of 3 with sodium methoxide. The reduction of 3 and 4 was carried out with different reduc