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Axonal transport defects: a common theme in neurodegenerative diseases

โœ Scribed by Subhojit Roy; Bin Zhang; Virginia M.-Y. Lee; John Q. Trojanowski


Publisher
Springer-Verlag
Year
2005
Tongue
English
Weight
470 KB
Volume
109
Category
Article
ISSN
0001-6322

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Defective axonal transport in motor neur
โœ Ali Morsi El-Kadi; Violetta Soura; Majid Hafezparast ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 359 KB

## Abstract Several recent studies have highlighted the role of axonal transport in the pathogenesis of motor neuron diseases. Mutations in genes that control microtubule regulation and dynamics have been shown to cause motor neuron degeneration in mice and in a form of human motor neuron disease.