## Abstract This review aims to summarize the current techniques to study myelination and remyelination in culture systems. We attempt to put these into historical context, and to identify the strengths and weaknesses of each approach, which vary depending on the experimental question to be tested.
Axonal signals in central nervous system myelination, demyelination and remyelination
✍ Scribed by Irène Coman; Gilles Barbin; Perrine Charles; Bernard Zalc; Catherine Lubetzki
- Book ID
- 119301695
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 230 KB
- Volume
- 233
- Category
- Article
- ISSN
- 0022-510X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
High dose corticosteroid (CS) administration is a common mode of therapy in treatment of acute relapses in multiple sclerosis (MS) but the effects of CS on remyelination and the cellular mechanisms mediating this repair process are controversial. We have examined CS effects on repair of toxin-induce
## Abstract Leukemia inhibitory factor (LIF) receptor signaling limits the severity of inflammatory demyelination in experimental autoimmune encephalomyelitis, a T‐cell dependent animal model of multiple sclerosis (MS) [Butzkueven et al. (2002) Nat Med 8:613–619]. To identify whether LIF exerts dir
## Abstract An increased level of myelin basic protein (MBP) degradation peptide 80–89, representative of myelin breakdown, is detected in myelinating foetal rat brain aggregate cultures supplemented with peritoneal macrophages at a time coinciding with the onset of myelination. During the period o