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In vitro modeling of central nervous system myelination and remyelination

✍ Scribed by Andrew A. Jarjour; Hui Zhang; Nina Bauer; Charles ffrench-Constant; Anna Williams

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
636 KB
Volume
60
Category
Article
ISSN
0894-1491

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✦ Synopsis

Abstract

This review aims to summarize the current techniques to study myelination and remyelination in culture systems. We attempt to put these into historical context, and to identify the strengths and weaknesses of each approach, which vary depending on the experimental question to be tested. We discuss the difficulty and importance of quantification of myelination and in particular remyelination. Finally, we provide our predictions of how these techniques will and should develop in the future. Β© 2011 Wiley Periodicals, Inc.

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