## Abstract Magnetization transfer imaging (MT) and localized proton spectroscopy (^1^HβMRS) were utilized in the evaluation of lesioins (high signal abnormalities on __T__~2~βweighted images) and normalβappearing white matter (NAWM) in multiple sclerosis (MI). Eleven patients with a clinical diagn
β¦ LIBER β¦
Axonal injury in the cerebral normal-appearing white matter of patients with multiple sclerosis is related to concurrent demyelination in lesions but not to concurrent demyelination in normal-appearing white matter
β Scribed by Sridar Narayanan; Simon J. Francis; John G. Sled; A.C. Santos; Samson Antel; Ives Levesque; Steven Brass; Yves Lapierre; Dominique Sappey-Marinier; G. Bruce Pike; Douglas L. Arnold
- Book ID
- 118489445
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 320 KB
- Volume
- 29
- Category
- Article
- ISSN
- 1053-8119
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## Abstract ## Purpose To explore ultrasmall superparamagnetic particles of iron oxide (USPIO) as a marker for diffuse inflammation in multiple sclerosis (MS) normalβappearing white matter (NAWM), using quantitative MRI. Disease activity in the NAWM of MS patients partly explains why MRI lesion bu