Axon growth inhibition: signals from the p75 neurotrophin receptor
β Scribed by Kaplan, David R.; Miller, Freda D.
- Book ID
- 109938730
- Publisher
- Nature Publishing Group
- Year
- 2003
- Tongue
- English
- Weight
- 163 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1097-6256
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## Abstract Previous studies have established that reciprocal interactions between the lowβaffinity p75 nerve growth factor (NGF) receptor (p75^NTR^) and the highβaffinity TrkA NGF receptor can dictate the cellular response to NGF. As the most important interaction, TrkA signaling was found to inhi
## Abstract The p75 neurotrophin receptor has been implicated in the regulation of multiple cellular functions that differ depending on the cell context. We have observed that p75^NTR^ is strongly induced on astrocytes as well as neurons in the hippocampal CA3 region after seizures; however, the fu