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Axial/equatorial proportions for 2-substituted cyclohexanones

โœ Scribed by Basso, Ernani A.; Kaiser, Carlos; Rittner, Roberto; Lambert, Joseph B.


Book ID
120643671
Publisher
American Chemical Society
Year
1993
Tongue
English
Weight
613 KB
Volume
58
Category
Article
ISSN
0022-3263

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Axial equatorial populations were determined for (E)-2-X-cyclohexanone oximes and O-methyl oxime ethers in chloroform by the Eliel method [X D F, Cl, Br, OCH 3 , N CH 3 2 , SCH 3 ]. A novel approach is presented, which uses 1 H NMR data from the protons bonded to C-6. The conformational proportions

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The preparation and characterization of tritium-labelled 2-(ochlorophenyl)-2-(methylamino) cyclohexanone hydrochloride is described. Under the exchange conditions employed (CF3COOH, 10 c3H20, P t ) , it was expected that the tritium wouldbe distributed between the phenyl and cyclohexanone rings. Our