Avermectin B1a: An irreversible activator of the γ-aminobutyric acid-benzodiazepine-chloride-ionophore receptor complex
✍ Scribed by Steven M. Paul; Phil Skolnick; Martin Zatz
- Book ID
- 118315045
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- English
- Weight
- 382 KB
- Volume
- 96
- Category
- Article
- ISSN
- 0006-291X
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The interaction of avermectin B1, (AVM) with the y-aminobutyric acid (GABA) receptor of rat brain was studied using radioactive ligand binding and tracer ion flux assays. Avermectin potentiated the binding of [3Hlflunitrazepam and inhibited the binding of both [3H]muscimol and [35Slf-butylbicyclopho
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