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Stimulation of benzodiazepine binding to rat brain membranes and solubilized receptor complex by avermectin B1a and γ-aminobutyric acid

✍ Scribed by Sheng-Shung Pong; Robert Dehaven; Ching Chung Wang

Book ID
115725141
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
609 KB
Volume
646
Category
Article
ISSN
0005-2736

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✍ Abalis, Ibrahim M. ;Eldefrawi, Amira T. ;Eldefrawi, Mohyee E. 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 729 KB

The interaction of avermectin B1, (AVM) with the y-aminobutyric acid (GABA) receptor of rat brain was studied using radioactive ligand binding and tracer ion flux assays. Avermectin potentiated the binding of [3Hlflunitrazepam and inhibited the binding of both [3H]muscimol and [35Slf-butylbicyclopho