Auxiliary mediated synthesis of aziridine-2-carboxylic acid derivatives
β Scribed by Philip Garnet; Ozdemir Dogan; Satish Pillai
- Book ID
- 103409213
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- French
- Weight
- 397 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The highly stereoselective ring opening of N-tosylaziridine 2-carboxylate esters with LiAIH4 followed by oxidation of the ensuing syn alcohols results in a highly efficient 4 step asymmetric synthesis of a-methyl I~-amino acids from N-sulfinylaziridine 2-carboxylate esters.
Aziridine 2-Carboxylate Ester Mediated Asymmetric Synthesis of Ξ±-Alkyl Ξ²-Amino Acids. -Highly stereoselective reductive ring opening of the N-tosylaziridines (II) with LiAlH4 followed by oxidation of the syn-amino alcohols (III) provides an efficient entry to the asymmetric synthesis of Ξ±methyl Ξ²-am