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AUU-To-AUG Mutation in the Initiator Codon of the Translation Initiation Factor IF3 Abolishes Translational Autocontrol of Its Own Gene (infC) in vivo

โœ Scribed by J. Scott Butler, Mathias Springer and Marianne Grunberg-Manago

Book ID
123634426
Publisher
National Academy of Sciences
Year
1987
Tongue
English
Weight
793 KB
Volume
84
Category
Article
ISSN
0027-8424

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The unusual translational initiation cod
The unusual translational initiation codon AUU limits the expression of the infC (initiation factor IF3) gene of Escherichia coli
โœ Brombach, Martin ;Pon, Cynthia L. ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Springer ๐ŸŒ English โš– 794 KB

The expression of infC, the structural gene for translational initiation factor IF3, has been studied in different constructs under the control of the lambda PL and tac promoters. The amount of synthesized IF3 has been determined by a quantitative functional test and the levels of IF3-specific mRNA