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Autosomal dominant familial spastic paraplegia is genetically heterogeneous and one locus maps to chromosome 14q

✍ Scribed by Hazan, Jamilé; Lamy, Catherine; Melki, Judith; Munnich, Arnold; de Recondo, Jean; Weissenbach, Jean


Book ID
109918219
Publisher
Nature Publishing Group
Year
1993
Tongue
English
Weight
496 KB
Volume
5
Category
Article
ISSN
1061-4036

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Novel locus for autosomal dominant pure
✍ Enza Maria Valente; Francesco Brancati; Viviana Caputo; Enrico Bertini; Clarice 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 93 KB 👁 2 views

Hereditary spastic paraplegia is a clinically and genetically heterogeneous disorder characterized by progressive spasticity of the lower limbs. Seven loci for autosomal dominant pure hereditary spastic paraplegia (ADPHSP) have already been mapped on chromosomes 14q, 2p, 15q, 8p, 12q, 19q, and 2q. W