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Autophagy-mediated anti-tumoral activity of imiquimod in Caco-2 cells

✍ Scribed by Jae Youn Yi; Yu-Jin Jung; Sun Shim Choi; Jungjin Hwang; Eunkyung Chung


Book ID
116298783
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
450 KB
Volume
386
Category
Article
ISSN
0006-291X

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## Abstract Osteosarcoma is a bone tumor that frequently develops during adolescence. 2‐Methoxyestradiol (2‐ME), a naturally occurring metabolite of 17β‐estradiol, induces cell cycle arrest and cell death in human osteosarcoma cells. To investigate whether the osteoprotegrin (OPG) protein plays a r