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Autophagy inhibition enhances ursolic acid-induced apoptosis in PC3 cells

✍ Scribed by Shin, S.W.; Park⁎, J.W.

Book ID
122694570
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
43 KB
Volume
53
Category
Article
ISSN
0891-5849

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## Abstract Ursolic acid (UA), a pentacyclic triterpenoid compound, has been demonstrated to have an antiproliferative effect in various tumors. We investigated the cell killing effects of UA in the human hormone refractory prostate cancer cell line, PC‐3 cells. Also, the molecular mechanisms under