Autonomic function and control of pancreatic somatostatin

✍ Scribed by E. Samols; J. I. Stagner; G. C. Weir

• Publisher: Springer
• Year: 1981
• Tongue: English
• Weight: 488 KB
• Volume: 20
• Category: Article
• ISSN: 0012-186X
• DOI: 10.1007/bf00254507

✦ Synopsis

In the canine pancreas alpha and beta adrenergic receptors exist on D cells with α stimulation inhibiting and β stimulation increasing somatostatin release. There are no dopaminergic receptors on D cells. Stimulation of muscarinic receptors causes mild inhibition of somatostatin secretion. Autonomic receptors on the D cell may be physiologically stimulated in vivo via local ganglionic and/or central autonomic drivers.