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Automatic analysis of the control of metabolic networks

✍ Scribed by Mustafa Bayram

Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 473 KB
Volume: 26
Category: Article
ISSN: 0010-4825
DOI: 10.1016/0010-4825(96)00011-x

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✦ Synopsis

In this paper we apply computer algebra techniques to analyze the control of metabolic networks. For this purpose, a computer program based on metabolic control theory was developed. When a stoichiometry matrix of the metabolic networks is given, the program calculates all the control coefficients (flux and metabolic control coefficients, summation and connectivity relationships) using elasticity coefficients. The program can be applied to any metabolic network which includes unlimited steps and intermediate metabolites.

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