A high throughput mass spectrometry based method is described for the determination of the 5-HT receptor agonist 31100, and its desmethyl metabolite, in human plasma. Samples were extracted using the MicroLutem system of solid phase extraction in the '96 well' format, automated by means of a robotic
โฆ LIBER โฆ
Automated solid-phase extraction and coupled-column reversed-phase liquid chromatography for the trace-level determination of low-molecular-mass carbonyl compounds in air
โ Scribed by P.R. Kootstra; H.A. Herbold
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 669 KB
- Volume
- 697
- Category
- Article
- ISSN
- 1873-3778
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A sensitive, specific, accurate and reproducible analytical method was developed and validated for the quantitation of the anticancer agent paclitaxel in human plasma. This procedure is based on high performance liquid chromatography/ion spray -tandem mass spectrometry. This methodology is highly sp