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Automated screening for metabolites in complex mixtures using 2D COSY NMR spectroscopy

✍ Scribed by Yuanxin Xi; Jeffrey S. de Ropp; Mark R. Viant; David L. Woodruff; Ping Yu

Book ID
106570982
Publisher
Springer
Year
2006
Tongue
English
Weight
321 KB
Volume
2
Category
Article
ISSN
1573-3882

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## Abstract Two‐dimensional diffusion ordered spectroscopy (DOSY) ^1^H NMR is proposed to analyze drugs that are complex mixtures in order to discriminate genuine from fake formulations. The method was applied to the analysis of 17 formulations of sildenafil, one being genuine Viagra and the others