Fine metal or metal oxide powder as an alternative to conventional organic matrices in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) has been utilized successfully for lower molecular mass analytes, poly(ethylene glycol) 200 (PEG 200) and methyl stearate.
Automated coupling of capillary-HPLC to matrix-assisted laser desorption/ionization mass spectrometry for the analysis of small molecules utilizing a reactive matrix
β Scribed by Stephan Brombacher; Stacey J. Owen; Dietrich A. Volmer
- Publisher
- Springer
- Year
- 2003
- Tongue
- English
- Weight
- 373 KB
- Volume
- 376
- Category
- Article
- ISSN
- 1618-2650
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Time-lag focusing matrix-assisted laser desorption/ionization mass spectrometry has been employed to analyse synthetic polymers with average molecular weights between approximately 3500 and 12 500 Da. Spectra are shown that demonstrate the improvement in resolution and sensitivity when time-lag focu