𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Autoimmunity to Collagen

✍ Scribed by David E. Trentham; Gary M. Kammer; W. Joseph Mccune; John R. David

Book ID
102751246
Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
629 KB
Volume
24
Category
Article
ISSN
0004-3591

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Thirty‐one patients with seronegative psoriatic arthritis, 27 patients with rheumatoid arthritis, 10 with psoriasis alone, and 20 normal volunteers were studied for autoimmunity to human collagens. Cellular and humoral responses were frequently observed in the 2 groups with arthritis, but the subjects without arthritis did not display reactivity to native collagens. These data demonstrate that collagens function as autoantigens in both psoriatic and rheumatoid arthritis.

πŸ“œ SIMILAR VOLUMES

Juvenile arthritis and autoimmunity to t
Juvenile arthritis and autoimmunity to type II collagen
✍ L. K. Myers; G. C. Higgins; T. H. Finkel; A. M. Reed; J. W. Thompson; R. C. Walt πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 79 KB πŸ‘ 1 views

Objective. Joint inflammation in juvenile rheumatoid arthritis (JRA) is sometimes associated with an autoimmune response to type II collagen (CII), a cartilage-specific protein. To test the hypothesis that down-regulation of autoimmunity to CII can be accomplished in JRA by oral administration of CI