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Autoimmunity: IL-21: a new player in Th17-cell differentiation

โœ Scribed by Deenick, Elissa K; Tangye, Stuart G


Book ID
110041463
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
131 KB
Volume
85
Category
Article
ISSN
0818-9641

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Background: Interleukin-21 (IL-21) is involved in T and NK cell activation and effector response and promotes Th17 cell differentiation. Here we investigated IL-21 receptor (IL-21R) expression in inflamed mucosa of inflammatory bowel disease (IBD) and evaluated its role in the induction of NK cell c