✦ LIBER ✦

IL-21 and TGF-β are required for differentiation of human TH17 cells

✍ Scribed by Yang, Li; Anderson, David E.; Baecher-Allan, Clare; Hastings, William D.; Bettelli, Estelle; Oukka, Mohamed; Kuchroo, Vijay K.; Hafler, David A.

Book ID: 109897487
Publisher: Nature Publishing Group
Year: 2008
Tongue: English
Weight: 271 KB
Volume: 454
Category: Article
ISSN: 0028-0836
DOI: 10.1038/nature07021

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Differentiation of human TH-17 cells doe

Differentiation of human TH-17 cells does require TGF-β!

✍ O'Garra, Anne; Stockinger, Brigitta; Veldhoen, Marc 📂 Article 📅 2008 🏛 Nature Publishing Group 🌐 English ⚖ 366 KB

IL-21 and IL-21R are not required for de

IL-21 and IL-21R are not required for development of Th17 cells and autoimmunity in vivo

✍ Ivo Sonderegger; Jan Kisielow; Reto Meier; Cecile King; Manfred Kopf 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 272 KB

TLR2-activated human langerhans cells pr

TLR2-activated human langerhans cells promote Th17 polarization via IL-1β, TGF-β and IL-23

✍ Ehsan Aliahmadi; Robert Gramlich; Andreas Grützkau; Manuel Hitzler; Melanie Krüg 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 333 KB

## Abstract The cytokines IL‐6, IL‐1β, TGF‐β, and IL‐23 are considered to promote Th17 commitment. Langerhans cells (LC) represent DC in the outer skin layers of the epidermis, an environment extensively exposed to pathogenic attack. The question whether organ‐resident DC like LC can evoke Th17 imm

TGF-β indirectly favors the development

TGF-β indirectly favors the development of human Th17 cells by inhibiting Th1 cells

✍ Veronica Santarlasci; Laura Maggi; Manuela Capone; Francesca Frosali; Valentina 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 268 KB

TGF-β and IL-6 drive the production of I

TGF-β and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell–mediated pathology

✍ McGeachy, Mandy J; Bak-Jensen, Kristian S; Chen, Yi; Tato, Cristina M; Blumensch 📂 Article 📅 2007 🏛 Nature Publishing Group 🌐 English ⚖ 620 KB

IL-6 programs TH-17 cell differentiation

IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

✍ Zhou, Liang; Ivanov, Ivaylo I; Spolski, Rosanne; Min, Roy; Shenderov, Kevin; Ega 📂 Article 📅 2007 🏛 Nature Publishing Group 🌐 English ⚖ 827 KB