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Autofocusing and ESI-MS analysis of protein digests in a miniaturized multicompartment electrolyzer

✍ Scribed by Roman Tomáš; Liushui Yan; Jana Křenková; František Foret

Book ID
102189383
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
483 KB
Volume
28
Category
Article
ISSN
0173-0835

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Derivatisation of arginine residues with
Derivatisation of arginine residues with malondialdehyde for the analysis of peptides and protein digests by LC-ESI-MS/MS
✍ Alexandra Foettinger; Alexander Leitner; Wolfgang Lindner 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 266 KB 👁 1 views

## Abstract In this study a selective tagging strategy for the derivatisation of arginine residues in peptides is presented. It is based on the reaction of the guanidine group of the arginine side‐chain with malondialdehyde (MDA) under strongly acidic conditions, in which a stable pyrimidine ring i