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A rapid HPLC/ESI-MS/MS method for quantitative analysis of isovalerylshikonin in rat plasma

✍ Scribed by MeiXiang Zhu; Yanbing Gao; Zhen Wu; YuFen Zhao


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
344 KB
Volume
24
Category
Article
ISSN
0269-3879

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## ABSTRACT In this work, a liquid chromatography coupled with electrospray ionization mass spectrometry (LC‐ESI‐MS) method was developed and validated for quantification of bile acids in fecal materials. Co‐eluting matrix impurities in fecal materials have been shown to greatly suppress the ioniza