Autocrine regulation of nerve growth factor expression by Trk receptors
β Scribed by Alessandra Mallei; Stuart J. Rabin; Italo Mocchetti
- Book ID
- 111178364
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 150 KB
- Volume
- 90
- Category
- Article
- ISSN
- 0022-3042
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Nerve growth factor (NGF) initiates the majority of its biological effects by promoting the dimerization and activation of the tyrosine kinase receptor TrkA. In addition to rapid increases in the phosphorylation of phosphatidylinositol 3Πkinase (PI 3-kinase) and phospholipase C-β₯ and increased ras a
In the rat, nerve growth factor (NGF) has been shown to affect immune reactivity by binding to cell surface receptors on a subpopulation of splenic mononuclear cells. This binding occurs in a specific and saturable fashion to what appear to be low-affinity (type 11) NGF receptors (NGFR). Immunofluor
Monoclonal antibodies (designated XIFl and IIIG5) recognizing distinct epitopes of the human truncated nerve growth factor receptor (NGF-Rt) were used in a two-site radiometric immunosorbent assay to monitor levels of NGF-Rt in human urine as a function of age. Urine samples were collected from 70 n