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Autistic Behavior, FMR1 Protein, and Developmental Trajectories in Young Males with Fragile X Syndrome

✍ Scribed by Donald B. Bailey; Deborah D. Hatton; Martie Skinner; Gary Mesibov


Book ID
110294844
Publisher
Springer US
Year
2001
Tongue
English
Weight
66 KB
Volume
31
Category
Article
ISSN
1573-3432

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The fragile X mental retardation 1 gene (FMR1) mutation is strongly correlated with specific and marked neurobehavioral and neuroanatomical abnormalities. The protein product, FMRP, is highly expressed in neurons of the normal mammalian brain, and absent or in low levels in leukocytes from individua