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Augmentation of antitumor immunity by genetically engineered fibroblast cells to express both B7.1 and interleukin-7

✍ Scribed by Tae S. Kim; Su W. Chung; Seung Y. Hwang


Book ID
117429824
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
220 KB
Volume
18
Category
Article
ISSN
0264-410X

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## Abstract Langerhans cells (LC) act as potent antigen‐presenting cells (APC) for primary and secondary T cell‐dependent immune responses. LC express several costimulatory and/or adhesion molecules such as B7/BB1, which has been implicated as one of the important determinants for professional APC.